FLUTICATONE VILO 100: Fluticasone Furoate & Vilanterol Uses
FLUTICATONE VILO 100 contains fluticasone furoate and vilanterol powder for inhalation and is marketed by Steris Healthcare. This inhaled combination contains an inhaled corticosteroid (fluticasone furoate) and a long-acting beta-2 agonist (vilanterol). Together, these medicines help reduce airway inflammation and maintain airway relaxation, supporting better control of persistent respiratory symptoms in appropriate patients.
This type of inhaler is generally used as maintenance therapy rather than as a rescue medicine for sudden breathing difficulty. It should be used regularly according to the healthcare professional's prescription, even when symptoms are controlled. Correct inhaler technique is important because the medicine needs to reach the lungs effectively.
What is FLUTICATONE VILO 100 For?
FLUTICATONE VILO 100 is formulated for maintenance treatment of chronic obstructive airway conditions such as asthma or chronic obstructive pulmonary disease (COPD) when an inhaled corticosteroid and long-acting bronchodilator combination is appropriate.
Fluticasone furoate helps control airway inflammation, while vilanterol provides prolonged bronchodilation.
The combination can help:
Reduce airway inflammation.
Relax airway muscles.
Improve airflow.
Reduce respiratory symptoms.
Support maintenance control of chronic airway disease.
Improve day-to-day breathing when used as prescribed.
The exact indication depends on the strength, formulation and approved prescribing information for the product. FLUTICATONE VILO 100 should not be used to treat a sudden asthma attack or acute episode of severe breathlessness unless specifically directed as part of an appropriate treatment plan.
Why is Fluticasone Furoate and Vilanterol Important?
Asthma and COPD can involve airway inflammation, narrowing and increased resistance to airflow. Effective maintenance treatment often requires both control of inflammation and sustained bronchodilation.
Fluticasone furoate is an inhaled corticosteroid that helps suppress inflammatory processes in the airways.
Vilanterol is a long-acting beta-2 adrenergic agonist that relaxes airway smooth muscle, helping keep the airways open for an extended period.
Using these complementary mechanisms in one inhaled formulation can provide convenient maintenance therapy for suitable patients.
Regular use is important because the treatment is designed to control underlying airway problems rather than provide immediate relief during a sudden attack.
Key Benefits
What Are the Benefits?
When appropriately prescribed and used correctly, FLUTICATONE VILO 100 may provide:
Long-acting bronchodilation.
Reduction of airway inflammation.
Better control of chronic respiratory symptoms.
Support for maintenance treatment of asthma or COPD.
Convenient once-daily combination therapy when prescribed that way.
Reduced need for separate maintenance inhalers in suitable patients.
Fluticasone Furoate Benefits
Fluticasone furoate reduces inflammatory activity in the respiratory airways. By controlling inflammation, it can help decrease airway swelling and sensitivity associated with chronic respiratory disease.
Vilanterol Benefits
Vilanterol stimulates beta-2 receptors in airway smooth muscle. This causes relaxation of the airway muscles and produces bronchodilation.
The combination therefore addresses two important components of chronic airway disease:
Fluticasone furoate → inflammation control
Vilanterol → prolonged bronchodilation
Side Effects
Like all medicines, fluticasone furoate and vilanterol powder for inhalation can cause side effects.
Possible side effects include:
Headache
Sore throat
Hoarseness
Cough
Oral or throat fungal infection (thrush)
Tremor
Muscle cramps
Increased heart rate
Mild respiratory irritation
Because fluticasone is an inhaled corticosteroid, rinsing the mouth with water and spitting it out after inhalation can help reduce the risk of oral thrush.
If side effects persist, become severe or interfere with normal activities, consult a healthcare professional.
Serious Side Effects
Serious reactions are uncommon but require prompt medical attention.
Seek urgent medical help for:
Severe difficulty breathing immediately after inhalation.
Swelling of the face, lips, tongue or throat.
Severe allergic reaction.
Chest pain.
Significant or irregular heartbeat.
Severe tremor or weakness.
Sudden worsening of respiratory symptoms.
Rarely, inhaled medicines can cause paradoxical bronchospasm, in which breathing suddenly becomes worse after inhalation. This requires immediate medical assessment.
Long-term corticosteroid exposure may also have systemic effects in susceptible individuals, particularly with higher doses.
Available Substitute
The appropriate substitute depends on the patient's diagnosis, inhaler strength, disease severity and prescribed treatment plan.
Potential alternatives may include:
Other fluticasone furoate/vilanterol inhalers.
Other inhaled corticosteroid/long-acting beta-2 agonist combinations.
Budesonide/formoterol inhalers.
Fluticasone/salmeterol inhalers.
Other guideline-appropriate maintenance inhalers.
These products are not automatically equivalent. Their active ingredients, doses, inhaler devices and dosing schedules can differ.
A healthcare professional should select a substitute rather than changing inhalers independently.
Dosage Guidelines
Use FLUTICATONE VILO 100 exactly as prescribed by your healthcare professional.
General inhalation guidance includes:
Use the inhaler at the prescribed frequency.
Inhale the medicine through the mouth using the correct technique.
Do not exceed the prescribed dose.
Do not use it as a replacement for an emergency rescue inhaler.
Use the inhaler regularly even when you feel well, unless your healthcare professional advises otherwise.
Keep the inhaler clean and store it according to the product instructions.
Do not share your inhaler with another person.
The exact dose depends on the formulation and clinical indication. Patients should follow the specific instructions supplied with their inhaler.
If you have difficulty using the device correctly, ask a healthcare professional or pharmacist to demonstrate the technique.
Precautions & Warnings
FLUTICATONE VILO 100 should be used with medical guidance in people with heart disease, abnormal heart rhythm, high blood pressure, diabetes, thyroid disorders, glaucoma, osteoporosis, seizures or a history of tuberculosis or other respiratory infections. Inform your healthcare professional about all medicines being taken, particularly other beta-agonists, corticosteroids, diuretics, beta-blockers or medicines that can affect heart rhythm. The inhaler is a maintenance medicine and should not be relied upon for immediate relief of a sudden severe asthma attack. Rinse your mouth and spit out the water after inhalation to reduce the risk of oral thrush. Patients should report worsening breathing symptoms or increased reliance on rescue medication. Do not discontinue long-term controller therapy without professional advice.
Mechanism of Action
Fluticasone furoate is an inhaled corticosteroid. It binds to glucocorticoid receptors in airway cells and influences the expression of inflammatory genes. This reduces the production and activity of various inflammatory mediators involved in airway inflammation.
Simplified:
Fluticasone furoate → glucocorticoid receptor activation → reduced inflammatory signaling → decreased airway inflammation
Vilanterol is a long-acting selective beta-2 adrenergic receptor agonist. It binds to beta-2 receptors on airway smooth muscle, activating intracellular signaling that increases cyclic AMP. This promotes relaxation of airway smooth muscle.
Simplified:
Vilanterol → beta-2 receptor stimulation → increased cAMP → airway smooth-muscle relaxation → bronchodilation
The combination therefore works through complementary mechanisms:
Fluticasone furoate → controls airway inflammation
Vilanterol → maintains airway relaxation
This dual action can help improve airflow and control chronic respiratory symptoms when the combination is clinically appropriate.
Conclusion
FLUTICATONE VILO 100, containing fluticasone furoate and vilanterol powder for inhalation, is marketed by Steris Healthcare as a combination maintenance inhaler for appropriate chronic respiratory conditions.
Fluticasone furoate helps reduce airway inflammation, while vilanterol provides prolonged bronchodilation by relaxing airway smooth muscle. Together, these actions can support improved airflow and ongoing symptom control in appropriately selected patients.
Correct inhaler technique and regular use are essential for achieving the intended maintenance effect. Because this is not generally a rescue treatment for sudden severe breathing difficulty, patients should follow their prescribed action plan for acute symptoms and seek urgent medical care when breathing becomes severely or suddenly worse.
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